TB-500 is a synthetic peptide of the naturally occurring healing protein Thymosin Beta 4. TB-500 has shown to increase the speed of wound healing, increase flexibility, reduce inflammation, enhance cell migration, and improve bone growth. The peptide’s therapeutic effect is due in large part from the peptide’s ability to regulate cell actin. Cell actin is a protein essential for healing and wound repair.

TB-500 Pre Mixed Peptide pen

  • Manufactured by: Hygehgh Biopharm Co., Ltd.
  • Country of origin: China
  • Manufactured since: 2009 – Present
  • Package :5mg /3ml /1 pen box
  • Purity:99%
  • Price: $1.3 – $3 per IU
  • Minimum Order:1 kits
  • Storage:2–8 ℃ in room temperature
  • Delivery: 5-15 days
  • Source: tophygetropin.com/shop/

TB 500 peptide is a type of wound healing peptide produced in the thymus gland, where it stimulates the synthesis of collagen and other proteins in the body. It’s also found in high concentrations in blood and tissues after injury. Research suggests that it can aid in repairing skin, cornea, and heart tissue.

TB 500 is an important substance found in high concentrations in damaged blood platelets. It is not a growth factor, but a major actin-regulating protein. TB-500 peptides have been used in research as a powerful anti-inflammatory agent and for the regeneration and remodeling of injured tissue.

Thymosin-Beta4 is a naturally occurring peptide found in human and animal cells that helps heal wounds, stimulate new growth and repair damaged tissue. Additionally, it has been shown to help heal chronic wounds as well as help stimulate the formation of new blood vessels.

Please be advised that the use of TB-500 for the purpose of muscle building is not only prohibited by WADA, but also by most other sporting organizations around the world. It is a banned substance under the category of “Peptide Hormones, Growth Factors, Related Substances and Mimetics (S2)”.

TB 500 Peptide benefit & effect

1. Accelerates Recovery from Injury

TB 500 accelerates recovery from injury by increasing the cell migration around the body and building new blood vessels. Both these events result in the increase in the supply of oxygen-rich blood to the damaged area, helping its tissues heal quickly and effectively. [R]

The creation of new blood vessels won’t only help you recover from injuries quickly. It might also reduce your blood pressure. There is ample research showing that the formation of new blood vessels often leads to a reduction in blood pressure, potentially saving you from heart disease.

2. Reduces Chronic Inflammation

According to a study conducted on human cornea, there is ‘mounting evidence’ that TB 4, which has the same properties as TB 500, has anti-inflammatory properties. The research also found that the peptide supplement can prevent the death of human corneal cells.

That is great news given that chronic inflammation can very dangerous for your health. It can trigger your immune system to attack your body’s healthy tissues and organs. Prolonged chronic inflammation can also increase your risk of cancer, heart disease, diabetes, rheumatoid arthritis and other diseases.

3. Improves Cardiac Function

Research has unearthed various ways TB 500 might improve cardiac function. This protein-peptide supplement might allow your heart to work better by playing a pivotal role in all the stages of heart vessel development, including vasculogenesis, angiogenesis, and arteriogenesis.

That’s not all. TB 4 has also been shown to promote the survival of cardiomyocytes, the cells that make the heart contract. Cardiomyocytes aren’t very easy to regenerate, so their prolonged survival is key to better heart health, something Thymosin Beta 4 manages to do with aplomb.

4. May Treat Brain Disorders and Injuries

According to a study carried out in 2015, Thymosin B4 promotes the plasticity of the central nervous system (CNS) and peripheral nervous system (CNS). This, the study concluded, directly led to recovery among the patients with a wide range of brain injuries and disorders.

Aside from that, treatment with the peptide supplement significantly improved behavioral and functional outcomes among the patients. The researchers involved in the study also concluded that TB4 could be used as a ‘potent’ anti-inflammatory agent to bring about neurological recovery.

5. Stimulates Hair Growth

Hair loss is a major problem these days. And it isn’t only men who will experience some form of hair loss during their lives. Health experts estimate that of the 80 million+ Americans affected by hair loss, almost 40% (or over 32 million) are women.

TB4 and, by extension, TB500 might help all these people. A study has found that TB4 increases hair growth by stimulating hair follicle stem cells, raising hopes that this protein peptide supplement might rectify the issue faced by hundreds of millions of people worldwide.

Combining TB 500 with RU-58841 usage would result in an extreme transformation, in which the user would be able to reverse hair loss up to 10 or even more years.

TB-500 Peptide side effect

There are many positive effects associated with Tb500 use, including enhanced recovery, reduced inflammation, and improved flexibility. The peptide works very effectively to aid recovery of slow healing injuries such as those to connective tissue, i.e. tendons and ligaments. Muscle injuries and injuries to skin are greatly helped as well. From reports from users and researchers around the globe, TB 500 seems to cause very few, if any, serious negative side effects.

Most peptides generally can produce a lightheadedness or nauseous feeling upon injection. Also, flu-like symptoms are prevalent among many other peptides as well. However, the incidence of these negative side effects occurring with TB500 administration is reported to be very low, if at all. TB 500 appears to be a very well tolerated peptide among users.

The information presented on this web site is not intended to take the place of your personal physician’s advice and is not intended to diagnose, treat, cure or prevent any disease.

How To Use The TB-500 ?

TB 500 Dosage and Cycle Guidelines

There are no officially sanctioned guidelines for TB 500 dosage. That’s because this supplement is yet to be approved by the FDA or any other regulatory authority around the world. We therefore suggest you consult your doctor to find out the TB 500 dosage that is right for you.

Here are the user-recommended TB 500 dosage guidelines:

For beginners: 5 mg per week, taken twice in seven days
For professionals: 20 mg per week, taken twice in seven days
While most users insist that a weekly 5 mg dose gives best results, some are of the view that taking between 15 mg and 20 mg is best.

TB 500 Cycle Guidelines


TB 500 cycle can be divided into two phases. The ‘loading phase’ lasts for the first 4 to 6 weeks, after which the ‘maintenance phase’ kicks in, which can last indefinitely.

Loading Phase Maintenance Phase
5 – 20 mg per week; 2-3 times per week
4 to 6 weeks 2.5 – 10 mg per week; 2-3 times per week
Indefinitely
Keep in mind that TB 500 is banned by the World Anti-Doping Agency (WADA) and the US Anti-Doping Agency (USADA), both in-competition and out of the competition. Athletes going to compete in national or international level competitions should therefore steer clear of this supplement.

How TB-500 Peptide works?

TB-500 works by increasing angiogenesis (blood vessel formation) around damaged tissue. See Philp D, Kleinman HK (April 2010). Animal studies with thymosin beta, a multifunctional tissue repair and regeneration peptide.

It also upregulates actin, a vital cellular protein critical to muscle contraction, cell mobility, and signaling between cells.See M. Santra (May 2014). Thymosin β4 Upregulation of MicroRNA-146a Promotes Oligodendrocyte Differentiation and Suppression of the Toll-like Proinflammatory Pathway.

TB-500 further enhances stem cell differentiation, cell mobility, and increases cell survival.

All of which equals better performance, fitness, and health for your animal.

The BEST TB-500 Dosage for Bodybuilders & Biohackers

The best dose of TB-500 is 100% dependent on the nature of your injury and how long your body will need to resolve it.

Some people will experience effects taking place much sooner, while others might need to give the TB-500 more time for its effects to kick in (assuming the dose and the injury are the same).

Unlike other therapeutic peptides on the market, there isn’t a universal dosing protocol for TB-500… so here’s what I recommend:

A) For treating an injury, inject 2.0-2.5 mg of TB-500 twice a week in evenly spaced doses (i.e. Monday, Thursday of a given week) for a total of 4-6 weeks, taking 2 weeks “off” before resuming another “on” cycle of 4-6 weeks.

You can have your injections be intramuscular or subcutaneous, but they DO NOT have to be precisely at the site of injury as TB-500 is distributed systemically.

(You can inject at the area of acute injury, but it is not mandatory for you to do so)

B) If you want a smaller dose delivered daily, go with 750 mcg once a day over a period of 3 months, cycling 3 months “on” and one month “off”

C) Same as B) but taking 3 mg of TB-500 every other day (EOD), which works due to TB-500’s half-life of ~2-4 days

D) If you just want to maintain and keep a strained area of the body supple, inject 2.0-2.5 mg of TB-500 subcutaneously once every two weeks (i.e. twice a month).

For what it’s worth, I’ve seen people manage to take some really high doses and tolerate them well for two straight weeks without any observable side effects (i.e. ~1.2 GRAMS of TB-500 over two weeks).

However, you will do just fine with the dosing protocols I’ve outlined here – pick one and stick with it.

Some people insist on a “loading phase” for TB-500 where you take a higher dose twice per week for 4-6 weeks before dropping down to a maintenance dose, but I have never had to use it.

Beginners should go with the lowest end of the dosing range, experienced people should stay in the middle, and those looking for the maximum healing effect should stick at the top of the range.

Injection Sites :Where To Injection The TB-500 Peptide ?

Mode of Administration: Subcutaneous injection to a fleshy part of the body, typically to the stomach or abdominal area. Ipamorelin can also be taken orally.

For faster recovery, it is advisable to inject in close proximity to injured areas.

How to Mix TB-500 Peptide?

  • Add 1mL of sterile water to the Peptide vial.
  • Release the water slowly and strictly on the side of the glass vial.
  • DON’T SHAKE the vial violently as this will disrupt the solution.
  • Continue to swirl until all the powder dissolves to achieve a clear solution.
  • For the TB-500 peptide pre mixed pen,Use it directly.

Storage Of The TB-500 Peptide

Store the product at room temperature in a non-humid environment. The vial should be shielded from light. An opened vial can be kept for up to 8 days refrigerated.

The Ipamorelin Mixed reviews Summary

TB-500 is one of the more interesting peptides on the market due to its potential for directly healing injuries. Some data, although limited, has also shown the peptide may in fact have heart-healing properties, particularly that of ventricle hypertrophy. However, because full data on TB-500 is so limited, it’s very hard to give an honest review beyond “he said she said.” But it’s also difficult to ignore that many users do tend to heal much faster with it than without, and in some cases, faster than would seem possible.

It’s also important to note that TB-500 users often report better results when used with Human Growth Hormone (HGH) or Human Growth Hormone Releasing Hormones (HGRH) compounds. This isn’t surprising when Growth Hormone (GH) is one of the primary healing tools we have at our disposal. It’s hard to say how much faster healing will be with or without a GH product, but what we know of GH (there is massive amounts of data available on GH) it only makes sense that it would be much faster.

TB-500 Peptide review

  • Availability
  • Reputability
  • Purity
  • Price
  • Cost Effectiveness