Proviron represents one of the oldest anabolic androgenic steroids on the market. A product of the giant pharmaceutical company Schering, it would first appear in 1934. Officially known as Mesterolone, it has appeared under numerous brand names over the years, but the Proviron name has continually remained dominant. It has also remained one of the most misunderstood anabolic steroids among steroid users.
Proviron (Mesterolone) Oral Steroids Tablets
- Manufactured by: Hygehgh Biopharm Co., Ltd.
- Country of origin: China
- Manufactured since: 2009 – Present
- Package :100 pills
- Price: $50–$90
- Minimum Order:1 bottle
- Storage:room temperature 15° to 30° C (59° to 86° F)
- Delivery: 5-15 days
- Source: tophygetropin.com/shop/
In many ways, Proviron is a very unique anabolic steroid. It shares some strong similarities to Masteron (Drostanolone) and to a degree Anavar (Oxandrolone) and Winstrol (Stanozolol) but in totality it is its own unique animal. In a performance capacity, Proviron is not used to promote large buildups in mass, although it can serve an important purpose during such a phase of training. We will, however, find Proviron to be far more common in cutting cycles, but once again its purpose will be somewhat unique.
As a therapeutic agent, Proviron is one of the most commonly used anabolic steroids in modern medicine. However, the Mesterolone hormone has never been approved by the U.S. FDA. It will primarily be found in European medicine, especially in Western Europe. The primary purpose of use is treating androgen deficiencies, age being the most common culprit of the condition. It is, however, also used in pre-pubescent males as well. The hormone is also used as a fertility aid in men and this alone makes it a very unique anabolic steroid as most anabolic steroids tend to have the opposite effect.
Proviron (Mesterolone) Functions & Traits:
Mesterolone is a dihydrotestosterone (DHT) derived anabolic androgenic steroid. Specifically it is a structurally altered DHT hormone possessing the addition of a methyl group at the carbon one position. This allows the hormone to survive oral ingestion by protecting it from hepatic breakdown. This is one of the only oral anabolic steroids that is not C17-alpha alkylated (C17-aa) but instead carries the added methyl group. Oral Primobolan is the other most well-known oral steroid that carries this same methyl group. While the added methyl group does in fact protect it from breakdown, the total bioavailability of Proviron will be far less than most all C17-aa oral steroids. For this reason it has fallen out of popularity among many performance enhancing athletes but as we will see perhaps unjustifiably so.
Proviron carries an androgenic rating of 30-40 and an anabolic rating of 100-150. All ratings derive from and are measured against testosterone, which carries a rating of 100 in both categories. Despite having an anabolic rating that is potentially greater than testosterone, Proviron will display very low anabolic traits. This is very similar to Halotestin (Fluoxymesterone), which carries a massive anabolic rating but very little translatable anabolic activity. In the case of Proviron, while structurally very anabolic, the Mesterolone hormone converts and reduces to Diol metabolites, in turn reducing anabolic activity. However, Proviron’s androgenic rating is a different story. In fact, its translatable androgenic activity appears to commonly be higher than its structural rating would imply.
On a functional basis, Proviron carries four primary traits that largely define its mode of action. First and foremost the Mesterolone hormone has a strong binding affinity to Sex-Hormone-Binding-Globulin (SHBG). In fact, it appears to be one of the strongest anabolic steroids in this regard. By binding to SHBG, a hormone partially responsible for reducing free testosterone, binding SHBG will enhance the amount of circulating free testosterone. More importantly for the anabolic steroid user, it will make a larger percentage of the anabolic steroids used available in a free rather than bound state. A simple way to look at it is the anabolic steroids you’re taking become more powerful and potent.
Proviron also has the ability to interact with the aromatase enzyme, the enzyme responsible for the conversion of testosterone to estrogen. By binding to the aromatase enzyme, Proviron can actually inhibit aromatase activity, thereby offering protection against estrogenic side effects. It will not carry an anti-estrogenic effect near the level of power of an Aromatase Inhibitor (AI) but it will be notable. Depending on the nature of the cycle the individual undertakes it is quite possible for Proviron to take care of all your anti-estrogen needs.
The Mesterolone hormone will also carry a strong binding affinity to the androgen receptor. Once again this will promote the functionality of other steroids to a degree but more importantly promote enhanced metabolic activity through direct lipolysis. Then we’re left with the final issue that surrounds Proviron as a fertility medication. This is an anabolic steroid that does not suppress gonadotropins similarly to other anabolic steroids. With minimal suppression and its extremely strong androgenicity, this will enhance sperm production as androgens are necessary to spermatogenesis stimulation. This not only enhances the amount of sperm produced but greatly and equally important enhances the quality of the sperm. Before we go any further understand Proviron does have the ability to suppress gonadotropins, but there’s a line that has to be crossed for notable suppression to interfere with sperm production. This will make sense once we dive into the side effects section.
Proviron (Mesterolone) benefit & effects
During a bulking phase Proviron is not going to be a foundational steroid, and for most men it will not have a place in an off-season cycle. There are exceptions and we’ll go over those here. Adding in Proviron could possibly help the individual breakthrough a sticking point during his cycle. At some point and time in all cycles the progress begins to wane, and in some cases come to a complete halt. By the way Proviron enhances the total free state of the other steroids being used in a stack, it could possibly help the individual breakthrough this sticking point. During the off-season, this is where most will use the largest amount of testosterone. Many will use large amounts during cutting cycles too, especially competitive bodybuilders but lower testosterone plans are more common during the cutting phase. However, there are those for numerous reasons who choose to run off-season cycles with limited testosterone doses. In such plans, including Proviron could give them a slight needed androgen boost. While it may not always be necessary it could prove to be beneficial.
Without question the best time to use Proviron will be during the cutting phase. This steroid has the ability to provide a bit of a hardening effect similar to Masteron, but more importantly the hardening effects of other steroids will be enhanced. Then we consider its strong binding to the androgen receptor, which will in fact enable the individual to burn body fat at a far more efficient rate. From here we must consider the anti-estrogen effect of Proviron. This will ensure the individual is less prone to water retention and as discussed, depending on the total cycle, it could negate the need for a traditional anti-estrogen. Then we’re once again left with the enhancement of circulating free testosterone. This can be a tremendous benefit when testosterone levels are often much lower during this phase of anabolic steroid use. In fact, with a low dosed testosterone cycle that includes other anabolic steroids, we can confidently say the total results will be greater for the individual who includes Proviron compared to the one who does not. In the end, the primary base benefit is the increased androgenicity of other steroids being used in order to promote a much harder and far more defined physique. It should be noted while Proviron can most certainly provide these traits they will not be noticeable unless you are lean.
Proviron (Mesterolone) side-effects
The side effects of Proviron, while adverse reactions are possible this truly represents one of the most well-tolerated anabolic steroids for the adult male. We will find many of the traditional negative effects associated with anabolic steroid use are impossible with this steroid. We will also find an issue that commonly surrounds oral steroids to be non-existent as well. However, once again possible side effects of Proviron most certainly exist, but safe and effective use is more than possible. With that in mind, let’s take a look at the possible side effects of Proviron and in doing so ensure safe supplementation.
Estrogenic Side Effects of Proviron:
Estrogenic side effects of Proviron do not exist. This anabolic steroid does not aromatize and is not a progestin making gynecomastia and excess water retention impossible. This will also reduce the probability of high blood pressure. High blood pressure is still possible, but it is unlikely for most men. The number one cause of high blood pressure among steroid users is heavy water retention, which is again impossible with this steroid. As a bonus, Proviron is actually anti-estrogenic in that it can inhibit the testosterone to estrogen conversion or at least significantly reduce it. In some stacks and cycles it could eliminate the need for a traditional anti-estrogen medication or at least reduce its total need.
Androgenic Side Effects of Proviron:
The possible androgenic side effects of Proviron include acne, hair loss and body hair growth. The androgenic side effects of Proviron are highly dependent on genetic predispositions; however, those who are predisposed will find sensitivity levels to be greater with this steroid than many others. However, it’s important to keep in mind if you are not predisposed such side effects of Proviron are impossible. If you are not predisposed to male pattern baldness hair loss will be impossible. If you are predisposed, while you’re going to lose your hair at some point no matter what you do the use of this steroid may speed up the rate of loss. The predisposition factor will also dictate the outcome as it pertains to acne and body hair growth. Important note – the 5-alpha reductase enzyme does not metabolize the Mesterolone hormone; there is no reduction to dihydrotestosterone (DHT), it’s already DHT. As a result, 5-alpha reductase inhibitors like Finasteride will not reduce or affect this steroid’s androgenicity and will offer no protection against androgenic effects. As it is significantly androgenic, the side effects of Proviron can include virilization in women; in fact, this anabolic steroid can promote such symptoms heavily. Virilization symptoms include body hair growth, a deepening of the vocal chords and clitoral enlargement. Virilization will be nearly impossible to avoid with this steroid and cannot be recommended to women.
Cardiovascular Side Effects of Proviron:
The cardiovascular side effects of Proviron are without question the most concerning as it pertains to this anabolic steroid. Baring any underlying issue, most men should not have an issue with blood pressure; however, despite the unlikelihood it’s always a good idea to keep an eye on it. Where the cardiovascular side effects of Proviron may prove problematic is with cholesterol; in fact, this steroid can be very harsh on cholesterol. If you have high cholesterol you must not supplement with this anabolic steroid. Data has shown the Mesterolone hormone can have a strong negative impact on cholesterol, both HDL cholesterol (good cholesterol) and LDL cholesterol (bad cholesterol). Studies have shown the use of this steroid has the ability to suppress HDL cholesterol upwards of 30% and beyond, as well as increase LDL levels by more than 60%. This represents a massive negative change in lipid values, and while it can be managed it will take an effort. If healthy cholesterol is to be maintained, the following tips and rules must be followed:
- You must NOT have high cholesterol
- You must keep an eye on your cholesterol
- You must be willing to discontinue use should cholesterol get out of control
- Your diet must be rich in omega fatty acids
- You should supplement with fish oil daily
- You should supplement with a cholesterol antioxidant supplement
- You should strictly limit the intake of saturated fats
- You should strictly limit the intake of simple sugars
- You should implement daily cardiovascular activity
Suppressive Side Effects of Proviron:
The side effects of Proviron will include the suppression of natural testosterone production, but it’s not as cut and dry compared to many steroids. The use of anabolic steroids, any anabolic steroid will suppress natural production; however, the rate of suppression varies greatly from one steroid to the next. In the case of Mesterolone, the total rate of suppression can be so minimal it can be insignificant. With standard Proviron doses, which normally fall in the 50-150mg per day range, the total suppression of natural testosterone production should be minimal of relatively no concern. When the dose surpasses the 150mg mark this will create a greater level of suppression, but there is no reason for any man to need a dose greater than 150mg per day. In theory, assuming your natural testosterone levels are in the high end optimal range, the individual could implement a cycle of Proviron and a moderate suppressive steroid at a low dose such as Anavar and forgo the need of exogenous testosterone supplementation. However, the Anavar dose would need to be very low and natural levels very high. Most men will still need exogenous testosterone, especially when we consider standard anabolic steroid cycles.
Hepatotoxic Side Effects of Proviron:
There are no liver related side effects of Proviron as this is not a hepatotoxic anabolic steroid. This is one of the only oral steroids on the market that is not C17-alpha alkylated (C17-aa) and as a result, liver damage or stress will be non-existent.
How To Use The Proviron (Mesterolone)?
Proviron doses are very difficult for many steroid users to plan, primarily because most do not understand how to use it or what its purpose of use is. With that in mind, you are encouraged to read the profile before you look at this dosing information. Gain a firm understanding of this steroid, what it can do and how it can benefit you before you consider a dosing plan. If this first step isn’t taking we assure you that you’ll be disappointed. If you have taken this first step, you’re ready to look at Proviron doses.
Therapeutic Proviron Doses:
In a medical setting, Proviron is used to treat male androgen deficiencies and fertility issues. In both cases, standard male Proviron doses will fall in the 50-75mg per day range. In the case of androgen deficiency the dose will almost always start at 75mg per day and adjust downward as needed. With 50-75mg Proviron doses, normally this is split into multiple 25mg doses per day.
Performance Proviron Doses:
For the purpose of performance enhancement, standard male Proviron doses will fall in the 50-150mg per day range. 50mg per day can provide a benefit, but most men will find Proviron doses in the 100-150mg per day range to be far more beneficial and very well-tolerated. No man should need a dose above and beyond 150mg per day; in fact, there is no benefit that can be obtained with higher doses that cannot be obtained with 150mg. This isn’t a principle that holds true with too many steroids, but it definitely holds true here.
Proviron Doses – Duration of Use:
In a therapeutic setting the duration of use is impossible to predict and will vary tremendously based on patient need. In a performance setting, regardless of the Proviron doses in question, the total duration of use will normally fall in the 8-12 week range. However, some may find short burst periods of use to be beneficial as this could aid in breaking through a sticking point during an off-season cycle or harden the individual up even more at the end of the cutting cycle. Remember, this steroid has the ability to greatly reduce SHBG, which will enhance the effectiveness of the other anabolic steroids being used.
Maximizing your Proviron Doses:
Once you decide on your Proviron doses, you’ll want to ensure you maximize the steroid’s use; get all you can out of it. This steroid will stack well with all anabolic steroids, but this doesn’t mean it needs to be used with all steroids. Without question Proviron will be the most beneficial during the cutting phase alongside steroids like Anavar, Masteron, Trenbolone and Winstrol. With such use, fat burning will be enhanced and the level of hardness that can be obtained greatly improved. You will want to keep your Proviron doses towards the high standard end in order to receive an adequate benefit. Remember, Proviron doses in the 100-150mg per day range will work best.
Storage Of The Proviron (Mesterolone)
Store at controlled room temperature 15° to 30° C (59° to 86° F)
Standard Proviron doses to treat androgen or male fertility will normally fall in the 50-75mg per day range. Normally the total dosing is split into 2-3 25mg doses per day. In androgen deficiency plans, the total dosing almost always starts at 75mg per day and slowly reduces to 25-50mg per day depending on patient need.
In a performance capacity, Proviron doses normally range from 50-150mg per day. Most men, however, will find 100mg per day to be the minimum beneficial dose with both 100mg and 150mg being highly effective. Total use will normally last between 8-12 weeks. However, in an effort to breakthrough a sticking point in a cycle, say towards the end of a cycle a 6 week course of Proviron may do the trick.
When you’re planning your Proviron use, you will find it stacks well with all anabolic steroids. During the cutting phase it will be most beneficial in conjunction with steroids like Anavar, Masteron and Winstrol as well as Primobolan. It will greatly promote the androgenicity of these steroids in order to provide and promote the hard look desired. In a bulking phase, while it will stack well with all anabolic steroids it’s hard to say if you’ll need it or not. Some will simply keep it on hand and include it when it proves to be possibly necessarily beneficial.
The Proviron (Mesterolone) Mixed reviews Summary
Proviron is not what we can call an extremely powerful anabolic steroid and we cannot really put it in a similar class that we would many other steroids. However, this is still a very beneficial anabolic steroid. It’s simply not beneficial in the traditional way in which we often view anabolic steroids. This is hard for many to accept, as message boards, while there are good ones many have brainwashed others into an improper view of anabolic steroids. In some ways, these individuals are just as guilty as the anti-steroid crowd when it comes to misinformation. Luckily for you, that should no longer be a problem when it comes to Proviron.
If used for the right purposes and with an understanding of the hormone, Proviron could potentially transform many of your cycles. Will this be the end all be all that sees a radical transformation acquired? Probably not, but it will provide benefits that others steroids cannot and simply round out your cycle in a way that will be hard to beat.
Proviron (Mesterolone) review
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